Thursday, February 27, 2014

Estrogen: Finally Good For Something!

By Todd Lee M.D.

Many bodybuilders use dry steroids and prohormones to try to avoid getting water bloat, mood swings and gynecomastia associated with estrogen. Some even take breast cancer meds to prevent aromatizing (wet) steroids from converting into estrogen at all! But they may be shortchanging themselves on gains. Since the 1960s Deca and D-bol were used to gain mass, It is said “ If you can’t grow on Deca and D-bol you can't grow.” Up until now this broscience has been sort of disregarded by sciency types, but the data exists to show why wet steroids and prohormones actually make you grow more muscle. A study in rats found that There are 2 estrogen receptors, type alpha and beta (ERA and ERB respectively). Turns out that when estrogen binds to ERA satellite cells migrate to muscle cells and donate a nucleus, and when estrogen binds to ERB, IGF-1 is expressed and we all know what that means….MUSCLE GROWTH! Thats right, estrogen directly stimulates muscle growth! This is supported in the evidence that women after menopause lose muscle if not given hormone replacement therapy.

In addition, Estrogen helps the muscle stave off the effects of post exercise inflammation, returning it to a ready-to-workout-again state.

So the next time you're going to dry yourself out to gain “lean mass” don’t, just bulk and be wet, you'll gain more muscle and you can handle more weight when your wet anyway!


For more details and references click here!

Wednesday, February 26, 2014

Best Prohormone 2013 - The Video





Read the rest of the article here!

Letrozole : King Of The Aromatase Inhibitors

If there is only one drug you use to boost your testosterone naturally it should be the breast cancer drug Letrozole (Femara). In a dutch study, Obese men with low testosterone and high estrogen were given just one 2.5mg dose per week with absolutely amazing results:



After just 6 weeks, LH, and FSH were more than doubled! This means Letrozole acts on the brain to increase the pituitary’s output of the hormones that signal the testes to produce sperm and testosterone.

Not surprisingly testosterone was increased, however it was quadrupled! thats Incredible! Obviously Estrogen was reduced as this is an Aromatase inhibitor and it was engineered to reduce estrogen. But no other Aromatase inhibitor or testosterone booster has had such dramatic effects. All told there was a tenfold reduction in the Estrogen:testosterone ratio.

The best part: the effects were almost as strong 6 months later.

In a Turkish study 2.5 mg were administered daily and surprisingly there was no increase to FSH and LH. additionally testosterone was only doubled, not quadrupled.



The estradiol level was reduced to half as it was in the once a week dosing study, so the final reduction in E:T ratio was only 5x.

Take home point is 2.5 daily counterintuitively does not work as well as 2.5 a week. My opinion is since the compound has a 3 day half life you're better off having 1 mg every 3 days for maximal T:E ratio!

For more info on how to restore normal function post cycle or just boost your natural testosterone click here!

[Fertil Steril. 2009 Aug;92(2):829.e1-2.]

Fertil Steril. 2010 Oct 8. [Epub ahead of print]

Eur J Endocrinol. 2008 May;158(5):741-7.

Tuesday, February 25, 2014

Anavar: The Best Medicine Ever Made!

Anavar: The Best Medicine Ever Made

By Todd Lee M.D.

Anavar is the old street name for Oxandrolone. It is my favorite medicine for healing for many reasons. Ready for the shocker? Its an Anabolic Steroid. You thought steroids were the Devil? You were wrong, at least in the case of Anavar. Unlike many oral steroids, which are typically damaging to the liver, it is actually FDA approved to TREAT liver issues. The worst side effect of normal steroids is a suppression of natural testosterone. But with Anavar once you stop taking it, your natural testosterone may go up!

Now that we cleared up that the normal side effects are virtually non existent lets get to the good stuff. Before it was discontinued because of the public’s witch hunt on anabolic steroids in the ‘80s due to baseball media nonsense, Anavar was used by medical doctors to treat burn victims, AIDS patients, and cut surgical recovery time in half. Additionally this compound has been shown in studies to permanently increase muscle mass and decrease fat mass directly and indirectly without diet or exercise. It inhibits cortisol activity and aromatase activity, basically preventing muscle wasting and fat gain. Effective doses are as low as 6 mg for men and 3 mg for women, but many bodybuilders take 100 mg or more a day. So when you hear comments about steroids and their side effects, keep in mind thats the effects of abuse not use. There is a big difference between having one shot of tequila and the whole bottle, ask anyone who got married in Vegas. In appropriate doses it could be the single best thing you could put in your body for the purpose of healing or improving your looks.

For the full article click here!

Friday, February 21, 2014

Letrozole : King Of The Aromatase Inhibitor

If there is only one drug you use to boost your testosterone naturally it should be the breast cancer drug Letrozole (Femara). In a dutch study, Obese men with low testosterone and high estrogen were given just one 2.5mg dose per week with absolutely amazing results:





After just 6 weeks, LH, and FSH were more than doubled! This means Letrozole acts on the brain to increase the pituitary’s output of the hormones that signal the testes to produce sperm and testosterone.

Not surprisingly testosterone was increased, however it was quadrupled! thats Incredible! Obviously Estrogen was reduced as this is an Aromatase inhibitor and it was engineered to reduce estrogen. But no other Aromatase inhibitor or testosterone booster has had such dramatic effects. All told there was a tenfold reduction in the Estrogen:testosterone ratio. 

The best part: the effects were almost as strong 6 months later.

In a Turkish study 2.5 mg were administered daily and surprisingly there was no increase to FSH and LH. additionally testosterone was only doubled, not quadrupled. 




The estradiol level was reduced to half as it was in the once a week dosing study, so the final reduction in E:T ratio was only 5x.

Take home point is 2.5 daily counterintuitively does not work as well as 2.5 a week. My opinion is since the compound has a 3 day half life your better off having 1 mg every 3 days for maximal T:E ratio!


Thursday, February 20, 2014

The Real Deal on Agmatine Sulfate

By Todd Lee M.D.

Im sure you've noticed all the new pre workout pump products have Agmatine sulfate in them now right? What you've probably heard is that it may or may not give a pump. Well it is a very confusing subject but I will make it easy. there are three versions of Nitric Oxide Synthase that Agmatine acts on. It inhibits the ones in your brain and heart, and activates the ones in your muscle capillaries. This means that Agmatine sulfate activates the enzyme that converts your traditional citruline and arginine based pump products into active nitric oxide in your muscle, but not elsewhere. Agmatine Sulfate amplifies the other pump products effectivenes!

The best time to take it isn’t pre-workout though, its first thing in the AM on an empty stomach. This also takes advantage of its growth hormone boosting effects. The pump benefit may take as much as 2 weeks to reach full effect but you will have an all day basal pump and pre workout Arginine will boost it to skin splitting levels!

Keto Diet: Carb-Free Dieting

By Todd Lee M.D.

0 carbs ever! Are you crazy? Well actually, yes. Yes I am. The Keto diet is sweeping the nation and for a good reason. It’s amazing in what it can do. Unlike previous 0 carb diets, the keto diet helps your body make particular molecules called ketone bodies from fat which fuel your brain. The brain is run almost exclusively on carbohydrates, but the rise and fall of blood sugar results in mood and energy fluctuations and disturbances. With the Keto diet, fuel is constant and steady so mood and energy are as well. Your body runs like a perfect machine and uses your body fat for fuel after a 2-6 week keto adaptation period. The trick is 80% of your calories come from fat! I know right! That sounds ridiculous, but it’s why all other 0 carb diets have failed in the past. By having a moderate amount of protein the liver you just convert your protein into carbs and you never convert over to Ketosis. If you want endless energy, to burn fat, and to be as healthy as humanly possible the keto diet is for you!

For more details click here!

H-DRL

By Todd Lee M.D.


H-Drol is the street name for 4-chloro-17a-methyl-androst-1,4- diene-3-17b-diol, AKA Halodrol 50 a prohormone to the Illegal steroid Turinabol. The name stems from the halogen gas chlorine at carbon number 4. as a 1,4 diene it behaves like an oral version of Boldenone AKA Equipoise: very mild. Although unlike EQ, there is no estrogen conversion. This means there is lean mass gains but no water bloat or other major side effects like the extra harsh M-Drol. It would be perfect but there is some liver toxicity from the 17 methylation like any oral steroid. Unfortunately it binds poorly to the androgen receptor, so it may not actually add anything when added to a stack with stronger steroids.

A legal and safe prohormone, H-DRL is available still and has not been banned yet.

You can find H-DRL here!

M-DROL Vs. M-DRL

By Todd Lee M.D.

M-Drol was the reincarnation of Superdrol, a highly toxic anabolic steroid mistaken for a prohormone. M-Drol was banned in 2012 for its harsh effects on the liver and cardiovascular system. It was popular because up until recently it was legal and over the counter. M-Drol would put 15 pounds of water on very quickly, storing the water in the muscle so it looked like real gains. However, as soon as you discontinued its use the water would leave the muscles and the gains would be lost. Unfortunately the compound stayed in the system for weeks and there was continued damage to the liver and cardiovascular system. This is on top of the normal side effects of hair loss, acne, and suppression of natural testosterone production.

The totally legal and safe alternative M-DRL has not been banned yet!

More information on M-DRL is available in our store at http://mind-and-muscle.myshopify.com/.

Wednesday, February 19, 2014

15% off your purchase at Mind and Muscle!


Thanks for finding us! Time to get your swell on! This offer is valid only through Saturday night at 11:59PM so don't hesitate! Visit our website at www.mindandmuscle.com and our online store at http://mind-and-muscle.myshopify.com/ . Happy lifting! 



Tuesday, February 18, 2014

Best Prohormones 2014

Dr. Todd Lee gives us his insights on this years best and worst prohormones!

M-Drol In Summary

By Todd Lee M.D.

M-Drol was the reincarnation of Superdrol, a highly toxic anabolic steroid mistaken for a prohormone. M-Drol was banned in 2012 for its harsh effects on the liver and cardiovascular system. It was popular because up until recently it was legal and over the counter. M-Drol would put 15 pounds of water on very quickly, storing the water in the muscle so it looked like real gains. However, as soon as you discontinued its use the water would leave the muscles and the gains would be lost. Unfortunately the compound stayed in the system for weeks and there was continued damage to the liver and cardiovascular system. This is on top of the normal side effects of hair loss, acne, and suppression of natural testosterone production.

For the full article, click here to visit our website!

Monday, February 17, 2014

The Best Prohormones of 2014

By Todd Lee M.D.

Here at mind and muscle all of our products are reasonably safe and 100% legal, thats not the case with other sites. The new wave of the effective prohormones are the andro class prohormones. Unlike 17 alpha methylated prohormones they are effective and safe.

These are the Best of 2014:

1-Androsterone: This was recently proven in a university study to put on mass and burn fat as well as previous studies have shown testosterone enanthate to do the same. This is a non aromatizing prohormone that converts to 1-testosterone. This is the new gold standard in prohormones. Lean mass or cutting perfection.

4-Androsterone: 4-AD converts to testosterone. This is the best way to get your testosterone up with prohormones. It does convert to estrogen so its perfect for a bulking cycle, or a lean mass when stacked appropriately.

Epiandrosterone: Epi-andro converts to DHT and is great as a hardener and to give strength, sex drive, and aggression. Excellent to keep you on your feet and fighting while cutting.

19 Nor Androsterone: This is a precursor to DECA, the king of bulking agents. If you can’t grow on DECA you can’t grow.

11 Oxo Androstenodione: This reduces cortisol activity to protect your muscles while cutting.

5 alpha OHP: A hardener which is considered to be similar to Winstrol for cutting and strength.

6-Keto-Dione: Helps you absorb nutrients and convert them into muscle, critical for lean mass building and stopping a bulking from just being a fattening.

Stacking is the best way to get results.

These prohormones do different things which work well together when mixed correctly to get synergistic results.

Bulking: 4 AD, 19 Nor, 6-keto with an aromatase inhibitor on hand incase you’re holding too much water (bloated face, high blood pressure).

Lean Mass: 1-AD and 6-keto. Add 4-AD if you are getting to dry (aching joints etc.) or not gaining size.

Cutting: 11-OXO, Epiandro, and 5a OHP. Add 1-AD if you’re losing your sex drive.

Thursday, February 13, 2014

MindandMuscle.com

Welcome to Mind and Muscle's blog page!
Here at Mind and Muscle we specialize in educating, informing, and providing you with all your prohormone and supplement needs!
We have supplements, articles, professional opinions, and anything else you need pertaining to bodybuilding and working out.  
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We will be updating with articles, videos, and pictures on a regular basis.
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