ACE-031

By Todd Lee M.D.

ACE-031 also known as ACVR2B is a monoclonal antibody against Myostatin.  Myostatin is a protein which stops your muscles from growing.  In mice born without Myostatin type 2b muscle fibers grow at an accelerated rate and to previously unknown proportions, But this is not the results of the experiments conducted with ACE-031!  

For some reason both Type 1 and Type 2 fibers grew.  This seems to indicate that the myostatin blocker, ACE-031, is blocking more than Myostatin.  Here is the reason: the monoclonal antibody has the head of the Activn receptor and the body of an antibody. Its a genetically engineered antibody against Myostatin right? wrong.  Although Myostatin is specific for this receptor, the receptor is not specific for myostatin.  It binds multiple members of the Transformation Growth Factor Beta (TGF-beta) family. Clearly other members of this family inhibit Type 1 fiber growth or else the antibody would not have allowed for the type 1 fibers to grow.  

What this means is by trying to make muscles grow by blocking myostatin we learned that myostatin does not act alone to inhibit muscle growth, but there is at least 1 other protein that works like myostatin to inhibit muscle growth that we were previously unaware of! This is huge!

For more details check out the full article here!  

Any questions? Email me Doctortoddlee@gmail.com or Find me on Facebook

Nothing in this article or on this site should be considered medical advice or as an endorsement to violate any law of the country in which you reside.  The information given is for fun and entertainment purposes only.  All claims are 100% dependent upon proper diet and exercise.  Please consult a medical practitioner prior to any diet and exercise program.